In SAP start transaction SM59 and select the RFC destination.
Use the function Extras>System Information>Target System:

Verify the System ID and Network Address of the system against the PC where ERP-Scale is installed:

Repeat this step multiple times to verify that the correct remote system is always used.
Resolution: Change the Program ID in SM59 under the registered server program:

and in ERP-Scale:

Ensure that the new Program ID is unique.
